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Reference Library

Biomarkers
Explained

Your blood test results, decoded. Search any biomarker below to understand what it measures, what your levels mean, and why it matters.

112 biomarkers

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Cholesterol

Cholesterol Panel

LDL, HDL & ApoB

Understanding the different types of cholesterol and what your ratio means for heart health.

Cholesterol

Lipoprotein Particles

ApoB & particle numbers

Why the number of lipoprotein particles matters more than cholesterol concentration alone.

Cholesterol

ApoB

Apolipoprotein B

The single best predictor of cardiovascular risk - and why your standard lipid panel might miss it.

Cholesterol

Lp(a)

Lipoprotein(a)

The genetic cholesterol marker most doctors don't routinely test - and why it matters.

Cholesterol

Triglycerides

Blood fat marker

What elevated triglycerides signal about your metabolic health and cardiovascular risk.

Blood Sugar

HbA1c

Glycated haemoglobin

Your 3-month average blood sugar - the gold standard for detecting pre-diabetes and diabetes.

Blood Sugar

Insulin Resistance

Fasting insulin & HOMA-IR

What your blood tests reveal about insulin resistance - before it shows up on a standard glucose test.

Hormones

Testosterone

Total & free testosterone

Understanding testosterone levels in both men and women - what's optimal and what affects it.

Hormones

Cortisol

Stress hormone

What your cortisol levels reveal about your stress response, sleep quality, and adrenal function.

Thyroid

Thyroid Panel

TSH, T3 & T4

How to read your thyroid results and what they mean for your energy, weight, and metabolism.

Inflammation

CRP

C-Reactive Protein

The body's key inflammation signal - what elevated CRP means and how to bring it down.

Inflammation

Inflammation Markers

CRP, ESR & more

Which blood tests reveal inflammation in your body - and what each one is actually measuring.

Inflammation

Homocysteine

Cardiovascular & brain health

High homocysteine is linked to heart disease and cognitive decline - and it's often completely fixable.

Liver

GGT

Gamma-glutamyl transferase

A sensitive liver marker that flags oxidative stress, alcohol use, and early liver stress before symptoms appear.

Kidneys

Creatinine

Kidney function marker

How creatinine and eGFR reveal the health of your kidneys - and what causes levels to rise.

Vitamins

Vitamin B12

Cobalamin

Why B12 deficiency is more common than you think and what low levels mean for your brain and energy.

Vitamins

Vitamin D

25-hydroxyvitamin D

The vitamin most Australians are deficient in - and what your blood levels actually mean for immunity and mood.

Vitamins

Omega-3 Index

EPA & DHA levels

Most people are low in omega-3. This test measures your levels and the impact on heart and brain health.

Vitamins

Ferritin vs Iron

Iron storage markers

The difference between serum iron and ferritin - and why ferritin is the more important number to watch.

Vitamins

Low Ferritin

Iron deficiency

What low ferritin means for your energy, hair, and performance - and when to act on it.

Minerals

Zinc

Serum zinc level

An essential trace mineral that supports immune function, wound healing, and testosterone production - deficiency is surprisingly common.

Minerals

Copper

Serum copper level

A trace mineral essential for enzyme activity, iron absorption, and nerve function - both deficiency and excess can cause harm.

Minerals

Magnesium

Serum magnesium level

Involved in over 300 enzymatic reactions - low magnesium affects sleep, muscle function, heart rhythm, and energy production.

Minerals

Calcium

Serum calcium level

The most abundant mineral in the body - measured in blood to assess bone health, parathyroid function, and cardiovascular risk.

Minerals

Calcium Corrected

Albumin-adjusted calcium

An adjusted calcium reading that accounts for albumin levels, giving a more accurate picture of true calcium status in the blood.

Minerals

Phosphate

Serum phosphate level

Works alongside calcium for bone strength and energy production - abnormal levels often signal kidney or parathyroid problems.

Minerals

Potassium

Serum potassium (electrolyte)

A critical electrolyte that regulates heart rhythm and muscle contractions - levels outside the normal range can be life-threatening.

Minerals

Chloride

Serum chloride (electrolyte)

An electrolyte that helps maintain fluid balance and acid-base equilibrium - often measured as part of a comprehensive metabolic panel.

Blood Count

Haemoglobin

Hb - oxygen-carrying protein

The protein in red blood cells that carries oxygen around the body - low haemoglobin is the hallmark of anaemia and causes fatigue.

Blood Count

Red Cell Count

RBC - erythrocyte count

The total number of red blood cells per volume of blood - used alongside haemoglobin to diagnose anaemia or polycythaemia.

Blood Count

Platelet Count

PLT - clotting cell count

Measures the number of clotting cells in your blood - low platelets increase bleeding risk while high levels can indicate inflammation or bone marrow issues.

Blood Count

Mean Platelet Volume

MPV - platelet size marker

Reflects the average size of platelets - elevated MPV can indicate increased platelet activity and is linked to cardiovascular and inflammatory conditions.

Blood Count

Haematocrit (PCV)

Packed cell volume %

The percentage of blood volume made up of red blood cells - a key indicator for anaemia, dehydration, and overall blood health.

Blood Count

MCV

Mean Corpuscular Volume

Measures the average size of red blood cells - abnormal values help identify the type of anaemia, whether from iron deficiency, B12, or folate.

Blood Count

MCH

Mean Corpuscular Haemoglobin

The average amount of haemoglobin per red blood cell - low MCH typically points to iron deficiency, while high MCH suggests B12 or folate deficiency.

Blood Count

MCHC

Mean Corpuscular Haemoglobin Concentration

The concentration of haemoglobin within red blood cells - an elevated MCHC can indicate hereditary spherocytosis or other red cell disorders.

Blood Count

Red Cell Distribution Width

RDW - red cell size variability

Measures the variation in red blood cell sizes - a high RDW suggests mixed nutritional deficiencies or early anaemia before other markers change.

Blood Count

Peripheral Blood Film

Blood smear morphology

A microscopic examination of blood cells that can reveal abnormal shapes, sizes, and types not captured by routine automated counts.

Blood Count

Total White Cell Count

WBC - leukocyte count

The total count of immune cells in your blood - elevated levels signal infection or inflammation, while low levels may indicate immune suppression.

Blood Count

Neutrophils

Neutrophil count

The most abundant white blood cells and your first line of defence against bacterial infections - counts rise with acute infection and stress.

Blood Count

Lymphocytes

Lymphocyte count

Immune cells that coordinate your body's response to viral infections and produce antibodies - abnormal counts can indicate viral illness or immune disorders.

Blood Count

Monocytes

Monocyte count

Large white blood cells involved in fighting chronic infections and clearing cellular debris - persistently elevated counts can point to ongoing inflammation.

Blood Count

Eosinophils

Eosinophil count

White blood cells that rise in response to allergies, asthma, and parasitic infections - elevated counts are a useful clue to allergic or eosinophilic conditions.

Blood Count

Basophils

Basophil count

The rarest white blood cells, involved in allergic reactions - elevated basophils may indicate allergic disease, hypothyroidism, or certain blood disorders.

Blood Count

ESR

Erythrocyte Sedimentation Rate

A simple test measuring how quickly red blood cells settle - a non-specific but reliable marker of inflammation, infection, or autoimmune disease activity.

Liver

Albumin

Serum albumin level

The most abundant protein in blood, made by the liver - low albumin signals poor nutrition, liver disease, or chronic illness.

Liver

ALP

Alkaline Phosphatase

An enzyme found in the liver, bile ducts, and bone - elevated levels can indicate liver disease, bile duct obstruction, or bone disorders.

Liver

ALT

Alanine Aminotransferase

The most liver-specific enzyme marker - elevated ALT is a key signal of liver cell damage from fatty liver, hepatitis, or medication toxicity.

Liver

AST

Aspartate Aminotransferase

An enzyme released when liver or muscle cells are damaged - used alongside ALT to assess liver health and rule out heart or muscle injury.

Liver

Bilirubin - Total

Total serum bilirubin

A waste product from the breakdown of red blood cells - elevated total bilirubin causes jaundice and can indicate liver disease or haemolysis.

Liver

Bilirubin Direct

Conjugated bilirubin

The processed form of bilirubin that the liver has conjugated - elevated direct bilirubin points specifically to liver disease or bile duct obstruction.

Liver

Bilirubin Indirect

Unconjugated bilirubin

The unprocessed fraction of bilirubin circulating in blood - high indirect bilirubin suggests haemolytic anaemia or benign conditions like Gilbert's syndrome.

Liver

Globulin

Serum globulin proteins

A group of proteins that includes antibodies and clotting factors - elevated globulin can indicate chronic inflammation, liver disease, or immune disorders.

Liver

Total Protein

Serum total protein level

The combined measure of albumin and globulin - reflects overall nutritional status and liver and kidney function.

Liver

Urea

Blood urea nitrogen (BUN)

A waste product from protein metabolism filtered by the kidneys - elevated urea indicates impaired kidney function or high protein intake.

Liver

Uric Acid

Serum urate level

The end product of purine metabolism - chronically high uric acid causes gout, kidney stones, and is linked to metabolic syndrome.

Liver

LDH

Lactate Dehydrogenase

An enzyme released when cells are damaged anywhere in the body - elevated LDH is a non-specific marker used to detect tissue injury, haemolysis, or cancer.

Liver

A/G Ratio

Albumin-to-Globulin Ratio

The ratio of albumin to globulin proteins - a low ratio can indicate chronic liver disease, immune disorders, or malnutrition.

Liver

Anion Gap

Calculated electrolyte balance

A calculated value from electrolytes that detects abnormal acid-base balance - a high anion gap signals metabolic acidosis from causes like kidney failure or diabetic ketoacidosis.

Liver

CO2 (Bicarbonate)

Serum bicarbonate level

Measures the main buffer that regulates the body's acid-base balance - abnormal bicarbonate levels indicate respiratory or metabolic pH disturbances.

Liver

Lipase

Pancreatic lipase enzyme

An enzyme produced by the pancreas to digest fats - significantly elevated lipase is the primary marker for acute and chronic pancreatitis.

Kidneys

eGFR

Estimated Glomerular Filtration Rate

The gold-standard estimate of kidney filtration capacity - used to stage chronic kidney disease and monitor kidney health over time.

Kidneys

Cystatin-C

Cystatin C kidney marker

A more sensitive marker of kidney filtration than creatinine - detects early kidney dysfunction before creatinine levels rise, unaffected by muscle mass.

Blood Sugar

Fasting Glucose

Blood glucose (fasted)

Blood sugar measured after an overnight fast - the first-line test for detecting pre-diabetes and diabetes, and assessing baseline metabolic health.

Cholesterol

HDL Cholesterol

High-Density Lipoprotein

The so-called "good" cholesterol that transports fats away from arteries to the liver - higher levels are protective against cardiovascular disease.

Cholesterol

LDL Cholesterol

Low-Density Lipoprotein

The primary cholesterol carrier in blood and the main driver of arterial plaque buildup - a key target for cardiovascular risk reduction.

Cholesterol

Total Cholesterol

Serum total cholesterol

The sum of all cholesterol fractions in the blood - useful as a screening number but best interpreted alongside HDL, LDL, and triglycerides.

Cholesterol

Trig/HDL Ratio

Triglyceride-to-HDL ratio

One of the best simple proxies for insulin resistance and cardiovascular risk - a high ratio signals metabolic dysfunction even when other markers look normal.

Cholesterol

HDL/LDL Ratio

HDL-to-LDL ratio

The balance between protective and atherogenic cholesterol fractions - used as a complementary cardiovascular risk indicator alongside absolute LDL levels.

Cholesterol

Apo A1

Apolipoprotein A1

The main protein component of HDL particles - a direct measure of your cardioprotective cholesterol carrier that may predict risk better than HDL concentration alone.

Cholesterol

ApoA1/B Ratio

Apolipoprotein A1-to-B ratio

The ratio of cardioprotective to atherogenic lipoprotein particles - considered one of the strongest predictors of cardiovascular disease risk.

Inflammation

hsCRP

High-Sensitivity C-Reactive Protein

A highly sensitive measure of systemic inflammation - low-level elevations predict cardiovascular disease risk years before symptoms appear.

Inflammation

IL-6

Interleukin-6

An inflammatory cytokine that drives the acute phase response - chronically elevated IL-6 is linked to cardiovascular disease, cancer, and metabolic syndrome.

Inflammation

Fibrinogen

Clotting and inflammation protein

A protein essential for blood clotting and an acute phase reactant - elevated fibrinogen signals chronic inflammation and increases cardiovascular and thrombosis risk.

Inflammation

RF Factor

Rheumatoid Factor

An autoantibody associated with rheumatoid arthritis and other autoimmune conditions - used alongside symptoms and anti-CCP to aid diagnosis.

Inflammation

Anti-CCP

Anti-Cyclic Citrullinated Peptide

A highly specific antibody marker for rheumatoid arthritis - often detectable years before joint symptoms appear, enabling early diagnosis and treatment.

Inflammation

MMA

Methylmalonic Acid

A sensitive marker of functional B12 deficiency that rises before serum B12 drops - elevated MMA confirms true cellular B12 insufficiency affecting nerve function.

Hormones

DHEA-S

Dehydroepiandrosterone Sulfate

An adrenal hormone that declines with age and serves as a precursor to sex hormones - low DHEA-S is associated with fatigue, reduced libido, and accelerated ageing.

Hormones

SHBG

Sex Hormone Binding Globulin

The protein that binds and transports testosterone and oestrogen - high SHBG reduces the amount of free, biologically active sex hormone available to tissues.

Hormones

Free Testosterone

Unbound bioavailable testosterone

The fraction of testosterone not bound to SHBG - often a more clinically meaningful measure than total testosterone for assessing symptoms of deficiency.

Hormones

FSH

Follicle Stimulating Hormone

A pituitary hormone that drives egg maturation in women and sperm production in men - elevated FSH in women is a key indicator of declining ovarian reserve or menopause.

Hormones

LH

Luteinising Hormone

The pituitary hormone that triggers ovulation in women and testosterone production in men - essential for assessing fertility and reproductive function.

Hormones

Oestradiol

E2 - primary oestrogen

The dominant form of oestrogen in women of reproductive age - critical for bone density, mood, fertility, and cardiovascular protection, declining sharply at menopause.

Hormones

Progesterone

Serum progesterone level

The hormone that dominates the second half of the menstrual cycle and supports early pregnancy - low progesterone can indicate anovulation or luteal phase deficiency.

Hormones

Prolactin

Serum prolactin level

The pituitary hormone responsible for milk production - elevated prolactin outside of pregnancy can suppress fertility and cause irregular periods in women and low testosterone in men.

Hormones

AMH

Anti-Müllerian Hormone

The best single measure of a woman's remaining egg supply - used to assess ovarian reserve, time fertility planning, and predict IVF response.

Hormones

FAI

Free Androgen Index

A calculated ratio of total testosterone to SHBG - a widely used indicator of androgen availability, particularly for assessing PCOS and androgen excess in women.

Hormones

IGF-1

Insulin-Like Growth Factor 1

The primary mediator of growth hormone's effects - a key marker of growth hormone status in both children and adults, and increasingly used in longevity medicine.

Hormones

Growth Hormone

Serum GH level

The pituitary hormone that drives tissue growth, muscle maintenance, and fat metabolism - deficiency in adults causes fatigue, body composition changes, and reduced quality of life.

Hormones

Parathyroid Hormone (PTH)

PTH - calcium regulator

The hormone that tightly controls blood calcium levels by regulating bone resorption and kidney calcium handling - abnormal PTH underpins many calcium and bone disorders.

Thyroid

FT3

Free Triiodothyronine

The active form of thyroid hormone that drives metabolism in every cell - low FT3 causes hypothyroid symptoms even when TSH appears normal.

Thyroid

FT4

Free Thyroxine

The main hormone secreted by the thyroid gland - FT4 is converted to active FT3 in tissues, and its level reflects the raw output of thyroid function.

Thyroid

Reverse T3

rT3 - inactive thyroid metabolite

An inactive form of thyroid hormone that can block FT3 receptors - elevated reverse T3 from chronic stress or illness may explain hypothyroid symptoms despite normal TSH and FT4.

Tumour Markers

PSA

Prostate Specific Antigen

A protein produced by prostate cells - elevated PSA prompts further investigation for prostate cancer, enlargement, or inflammation, and is a key men's health screening tool.

Tumour Markers

CA-125

Cancer Antigen 125

A protein marker elevated in ovarian cancer - used to monitor treatment response and detect recurrence, though it can also rise in benign conditions like endometriosis.

Vitamins

Folate

Vitamin B9 - folic acid

Essential for DNA synthesis and red blood cell formation - low folate causes megaloblastic anaemia and is critical for neural tube development in early pregnancy.

Vitamins

Active B12

Holotranscobalamin (HoloTC)

The biologically active fraction of B12 that cells can actually use - a more sensitive early marker of B12 deficiency than standard serum B12 testing.

Vitamins

1,25-Dihydroxy Vitamin D3

Calcitriol - active vitamin D

The fully activated form of vitamin D that regulates calcium absorption - measured when kidney disease, granulomatous conditions, or vitamin D metabolism disorders are suspected.

Vitamins

CoQ10

Coenzyme Q10 (ubiquinol)

A vital antioxidant for mitochondrial energy production - levels decline with age and statin use, making it important for anyone experiencing unexplained fatigue or muscle symptoms.

Vitamins

NAD+/NADH Ratio

Nicotinamide adenine dinucleotide

A measure of cellular energy metabolism and redox balance - declining NAD+ is a hallmark of ageing and is a central target in longevity research.

Fatty Acids

Omega-3 Index (EFA)

EPA + DHA as % of red cell membranes

The percentage of EPA and DHA in red blood cell membranes - a validated measure of long-term omega-3 status and a predictor of heart disease and cognitive health risk.

Fatty Acids

Omega-3/6 Ratio

Omega-3 to omega-6 balance

The balance between anti-inflammatory omega-3s and pro-inflammatory omega-6s - most Western diets are highly skewed toward omega-6, driving chronic inflammation.

Fatty Acids

Omega-3

EPA & DHA fatty acids

Measures the absolute level of omega-3 fatty acids (EPA and DHA) in the blood - essential for reducing cardiovascular risk, supporting brain function, and controlling inflammation.

Fatty Acids

Omega-6

Omega-6 fatty acids level

Measures the level of omega-6 fatty acids, which compete with omega-3s - excess omega-6 from processed seed oils is a driver of chronic low-grade inflammation.

Iron

Iron

Serum iron level

The amount of iron circulating in the bloodstream at the time of testing - best interpreted alongside ferritin and TIBC to understand total iron status.

Iron

Iron Saturation

Transferrin saturation (TSAT)

The percentage of transferrin (iron-carrier protein) that is loaded with iron - low saturation confirms iron deficiency, while very high saturation raises concern for iron overload (haemochromatosis).

Iron

TIBC

Total Iron Binding Capacity

Measures the maximum amount of iron the blood can carry via transferrin - elevated TIBC indicates the body is hungry for more iron, consistent with iron deficiency anaemia.

Coagulation

Prothrombin Time

PT / INR - clotting speed test

Measures how long blood takes to clot via the extrinsic pathway - used to monitor warfarin therapy, assess bleeding risk, and evaluate liver function.

Immune

IgA

Immunoglobulin A

The antibody that guards mucosal surfaces like the gut and respiratory tract - low IgA is associated with recurrent infections and is required before accurate coeliac antibody testing.

Immune

Mercury

Blood mercury level

A neurotoxic heavy metal that accumulates from high fish consumption and environmental exposure - elevated blood mercury can impair cognitive function, immune health, and the nervous system.

Genetics

MTHFR Genotyping

Methylation gene variant test

Tests for common variants in the MTHFR gene that reduce the ability to process folate and recycle homocysteine - relevant for cardiovascular risk, pregnancy planning, and methylation support.

Inflammation

pTau

Phosphorylated tau - brain marker

An emerging blood biomarker for Alzheimer's disease - elevated phosphorylated tau reflects tau tangle pathology in the brain and is being validated as an early detection tool for neurodegeneration.

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